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    Pearl
    De La O Cantina, Restaurant in Guadalajara
    Restaurant150Points

    De La O Cantina

    1403900011325, Guadalajara

    Restaurant in Guadalajara, Mexico

    The Read

    Dress

    Casual

    Why go

    De La O Cantina is a useful Col Americana pick when timing and a relaxed cantina setting matter more than a formal restaurant format. It is strongest for lunch, dinner, or late social plans on most days, but Tuesday closure matters. For a more food-led Guadalajara meal, compare it with Tikuun Comedor Local, Xokol, Hueso Restaurante, Restaurante Demetria, or Teté Cocina De Barrio.

    About De La O Cantina

    In Guadalajara, De La O Cantina is a practical option to consider when timing and a casual dress code matter. Its schedule is the main reason to keep it on a plan: it opens at 1 PM on most operating days, runs late most nights, is closed on Tuesday.

    Choose it for a relaxed late plan

    Plan for a casual venue with late hours rather than building the night around a particular cuisine, signature dish, pricing structure, or tasting-menu format.

    For a broader Guadalajara dining plan, compare it with Tikuun Comedor Local, Xokol, Hueso Restaurante, Restaurante Demetria, Teté Cocina De Barrio. Those are useful cross-shops when you are deciding the tone of the outing; De La O Cantina is easiest to place when timing and a casual setting are the priorities.

    Useful for Guadalajara plans that may run late

    De La O Cantina is in Guadalajara. Monday, Thursday, Friday, Saturday, Sunday hours are 1 PM to 1 AM; Wednesday runs 1 PM to 12 AM; and Tuesday is closed. That schedule makes it especially relevant for later plans, while the casual dress code keeps the commitment low.

    For wider planning, use our full Guadalajara restaurants guide, plus the city guides for Guadalajara hotels, Guadalajara bars, Guadalajara wineries, Guadalajara experiences. Restaurant research can also include other Guadalajara dining rooms, depending on the style of outing you want.

    The takeThis is a neighbourhood spot built for easy, social occasions: after-work drinks, casual hangouts and group nights where sharing and conversation are part of the point. The communal tables and bar seating invite groups and strangers to mingle, and the cantina's emphasis on everyday local traditions makes it less a formal dinner destination than a convivial place for tacos and cocktails. Expect an energetic, sociable evening rather than a hushed, table-by-table tasting.
    Also considerAlternatives
    Restaurant contextGuadalajara, Mexico
    Explore GuadalajaraNearby
    Around this placeMore Pearl picks

    Planning details

    Location
    Calle Argentina 70, Col Americana, Americana, 44200 Guadalajara, Jal., Mexico
    Website
    instagram.com
    Phone
    +523319749782
    The take

    The Take

    The Vibe

    De La O Cantina leans on Colonia Americana's early twentieth-century architecture to set its mood: high ceilings, tiled floors and the cadence of a historic façade make the room feel anchored in the city's past. The cantina format functions as a civic living room, favouring shared tables and bar-adjacent counters that encourage side-to-side conversation. That social logic makes the space lively and intimate at once — not quiet by design — while its rootedness in neighbourhood rhythm gives it a comfortable, classic character rather than a heavily styled one.

    Best For

    This is a neighbourhood spot built for easy, social occasions: after-work drinks, casual hangouts and group nights where sharing and conversation are part of the point. The communal tables and bar seating invite groups and strangers to mingle, and the cantina's emphasis on everyday local traditions makes it less a formal dinner destination than a convivial place for tacos and cocktails. Expect an energetic, sociable evening rather than a hushed, table-by-table tasting.

    Ordering Tips

    Lean into the cantina's strengths by ordering shareable plates and cocktails. The menu highlights bold options—Chicharrón and chorizo-and-potato tacos—alongside punchy seafood like aguachile tatemado, all of which are suited to passing around at a long table. Don’t skip the signature cocktails (Pepita Tequila Mai Tai and the Zombi) to complement the food. Because seating encourages lateral conversation, pace your orders so plates arrive in waves for the table to share.

    Planning details

    Location

    Calle Argentina 70, Col Americana, Americana, 44200 Guadalajara, Jal., Mexico · Directions

    +523319749782

    instagram.com

    Also consider

    Where to look if this does not fit

    If the plan needs a more food-led Guadalajara dinner, try Tikuun Comedor Local or Xokol. If the occasion calls for a more polished room, compare Hueso Restaurante and Restaurante Demetria.

    Restaurant context

    How it compares in Guadalajara

    De La O Cantina makes sense when ease and late-hour flexibility are the priority. Tikuun Comedor Local and Xokol are better choices when the meal needs to feel more food-led, especially for diners comparing Guadalajara restaurants around regional cooking rather than a cantina-style night.

    Hueso Restaurante and Restaurante Demetria are stronger cross-shops for a more designed room or polished special-occasion plan. De La O Cantina is the easier recommendation when the group wants a relaxed Americana base and less ceremony.

    Teté Cocina De Barrio is the closer alternative for readers who want neighborhood-restaurant energy instead of a cantina frame. Pick De La O Cantina for a later, looser night; pick Teté when dinner should feel more compact and meal-focused.

    Explore Guadalajara
    Around this place
    Read more on Pearl

    Discover more on Pearl

    Unlock the full De La O Cantina guide in Pearl, including awards, comparisons, FAQs, planning details, and nearby places.

    Compare De La O Cantina
    De La O Cantina Guadalajara and similar venues
    VenueLocationAwards
    De La O CantinaGuadalajaraNo published awards
    Tikuun Comedor LocalGuadalajaraNo published awards
    XokolGuadalajara
    Michelin Guide Mexico 20262025 The Best Chef Two Knives
    Hueso RestauranteGuadalajaraNo published awards
    Restaurante DemetriaGuadalajaraNo published awards
    Teté Cocina De BarrioGuadalajaraNo published awards

    How De La O Cantina Guadalajara compares with similar nearby venues.

    FAQ

    Frequently Asked Questions

    Can I eat at the bar at De La O Cantina?

    For bar seating, check with De La O Cantina directly. It is in Guadalajara, has a casual dress code, keeps late hours on most operating days.

    Can De La O Cantina accommodate groups?

    If you are planning with several people, confirm directly before relying on it; Restaurante Demetria or Tikuun Comedor Local may also be worth comparing for a different kind of night out.

    How far ahead should I book De La O Cantina?

    For reservations, check directly and plan around the schedule: Monday, Thursday, Friday, Saturday, Sunday run from 1 PM to 1 AM; Wednesday runs from 1 PM to 12 AM; and Tuesday is closed.

    Is lunch or dinner better at De La O Cantina?

    De La O Cantina opens at 1 PM on operating days and runs into the late evening or night, depending on the day. Choose based on timing.

    Is De La O Cantina good for a special occasion?

    It can be considered for a casual occasion, thanks to the casual dress code and late hours. If the occasion needs a more defined restaurant plan, Xokol or Hueso Restaurante may be useful comparisons.

    What are alternatives to De La O Cantina in Guadalajara?

    Start with Xokol or Tikuun Comedor Local if you want to compare it with other Guadalajara restaurants, also look at Hueso Restaurante, Restaurante Demetria, Teté Cocina De Barrio when choosing the tone of the outing.