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    Pearl
    Elixir, Bar in San Francisco
    Bar200Points

    Elixir

    Mission, San Francisco

    Bar in San Francisco, United States

    Why go

    Elixir is a practical Mission pick for a casual San Francisco drink when flexibility matters more than a polished cocktail-room plan. Go earlier for easier conversation, later for more energy, compare it with ABV or Last Rites if the night calls for a more cocktail-led or themed experience.

    About Elixir

    Elixir is a casual San Francisco venue with hours that make it useful for evening plans and later nights on select days. The most grounded way to plan around it is simple: check the day's posted hours and keep the dress code casual.

    For a first visit, timing is the most reliable planning factor. Elixir opens at 4 PM Monday through Friday, at 12 PM on Saturday, at 2 PM on Sunday. It closes at 10 PM on Monday and Sunday, at 12 AM on Tuesday and Wednesday, at 2 AM on Thursday, Friday, Saturday.

    Plan it as an easy San Francisco stop, not a polished splurge

    The case is direct: choose Elixir when casual dress and the posted hours fit the plan. Do not expect a full dining format, tasting structure, outdoor setup, specific price point, or particular beverage program when deciding whether it suits the night.

    For a broader night in San Francisco, pair this kind of stop with the San Francisco bars guide rather than treating one venue as the entire itinerary. If dinner is part of the decision, use the San Francisco restaurants guide to build around the city. Visitors planning a fuller trip can also check the San Francisco hotels guide.

    How to decide if this is your night

    Pick Elixir for a casual San Francisco plan when the posted hours line up with your schedule. If you want to compare the mood or format before deciding, look at ABV, Last Rites, or Churchill Cocktail Bar as other options to consider.

    The practical verdict: Elixir works when the night needs flexible timing and a casual dress code. Use the hours as the main starting point and check current venue details before making it the center of the evening.

    The takeThis is a bar for people who value place over pretense. It suits after‑work drinks, casual hangouts, and late‑night conversations with friends or fellow locals, especially for those who appreciate historic character and a low‑key setting. Patrons come for steady company rather than spectacle: the sort of spot where regulars gather, newcomers blend in, and the conversation is the point. It’s not about technical cocktail theater here but about the social glue of a neighbourhood saloon that has lasted generations.
    Venue detailsSeated Bar
    Also considerAlternatives
    Bar contextSan Francisco, United States
    Explore San FranciscoNearby

    Planning details

    Location
    3200 16th St, San Francisco, CA 94103
    Website
    elixirsf.com
    Phone
    +1 415 552 1633
    Around this placeMore Pearl picks
    The take

    The Take

    The Vibe

    Elixir feels like a neighborhood anchor rooted in San Francisco history. The bar occupies a Victorian corner building and leans into a lived-in, wood‑lined interior with low light and an acoustic warmth that only long use can produce. It reads less like a designed cocktail lab and more like a saloon with institutional standing — unpretentious, timeworn, and quietly confident. The atmosphere celebrates continuity: decades of conversation, changing neighborhoods, and a sense of endurance that turns the room itself into the main attraction.

    Best For

    This is a bar for people who value place over pretense. It suits after‑work drinks, casual hangouts, and late‑night conversations with friends or fellow locals, especially for those who appreciate historic character and a low‑key setting. Patrons come for steady company rather than spectacle: the sort of spot where regulars gather, newcomers blend in, and the conversation is the point. It’s not about technical cocktail theater here but about the social glue of a neighbourhood saloon that has lasted generations.

    Venue details

    Ambiance

    Lived-in dive bar atmosphere with warm pub appeal, buzzy evenings, and Wild West roots featuring the original mahogany back bar.

    Tags

    Vibe

    ClassicCozyHistoric

    Best For

    After WorkCasual HangoutLate Night

    Experience

    Historic Building

    Format

    Seated Bar

    At the Bar

    Late Night
    Open Until 2am
    Music
    Upbeat

    Signature Pours

    • Boot Black Stout
    • Napa Creole
    Planning details

    Location

    3200 16th St, San Francisco, CA 94103 · Directions

    +1 415 552 1633

    elixirsf.com

    Also consider

    Also Consider

    • ABV, Notable alternative
    • Little Star Pizza, Notable alternative
    • Lore, Notable alternative
    • Churchill Cocktail Bar, Notable alternative
    • Last Rites, Cocktails, Cocktails
    Bar context

    How It Compares

    Elixir is the easier, lower-pressure choice if the plan is a casual Mission drink rather than a destination cocktail night. ABV is the better comparison for readers who want the drink program to drive the evening; choose Elixir when convenience and a relaxed bar feel matter more than a more structured cocktail agenda.

    Last Rites is the stronger pick for a themed cocktail night, while Elixir makes more sense for a first stop, last drink, or mixed group that does not want the room to define the whole evening. Churchill Cocktail Bar sits closer to the classic bar-night lane, so compare based on mood and location rather than assuming one replaces the other.

    If food is part of the plan, Little Star Pizza is the more practical choice for a group that needs dinner with the outing. Lore is worth cross-shopping when the group wants a different San Francisco bar setting, but Elixir is the simplest call when the priority is an easy Mission round with minimal planning friction.

    Explore San Francisco
    Around this place
    Read more on Pearl

    Discover more on Pearl

    Unlock the full Elixir guide in Pearl, including awards, comparisons, FAQs, planning details, and nearby places.

    Compare Elixir
    Elixir San Francisco and similar venues
    VenueLocationCuisineAwards
    ElixirSan Francisco; No published awards
    ABVSan Francisco;
    2026 OAD Casual in North America Recommended2026 Eater San Francisco Best Cocktail Bars2025 OAD Casual in North America Ranked · #8522024 OAD Casual in North America Ranked · #8352022 North America's 50 Best Bars · #392017 World's 50 Asia's Best Bars · #452017 World's 50 Best Bars · #462016 World's 50 Asia's Best Bars · #142016 World's 50 Best Bars · #36
    Little Star PizzaSan Francisco; No published awards
    LoreSan Francisco; No published awards
    Churchill Cocktail BarSan Francisco; No published awards
    Last RitesSan FranciscoCocktailsNo published awards

    How Elixir San Francisco compares with similar nearby venues.

    FAQ

    Frequently Asked Questions

    What's the best time to go to Elixir?

    Use the posted hours as the main guide. Elixir opens at 4 PM Monday through Friday, 12 PM on Saturday, 2 PM on Sunday. It closes at 10 PM on Monday and Sunday, 12 AM on Tuesday and Wednesday, 2 AM on Thursday, Friday, Saturday.

    Is Elixir open late?

    Yes. Elixir is open until 2 AM on Thursday, Friday, Saturday, until 12 AM on Tuesday and Wednesday. Monday and Sunday close earlier at 10 PM.

    What's the crowd like at Elixir?

    The dress code is casual, but specific crowd details are not available. If atmosphere is the deciding factor, compare Elixir with Churchill Cocktail Bar or Lore, or check current venue channels before you go.