Restaurant in Isola Sant'Antonio, Italy
Rooted regional cooking at honest prices.
Da Manuela earns its 2025 Michelin Plate with country cooking rooted in Lower Piedmont and Lomellina tradition: rabbit with vegetables, freshwater fish, frogs' legs, and a strong local cheese board at the €€ price point. With a 4.7 rating from over 1,385 reviews, it is one of the most reliable value propositions for honest regional Italian cooking in the Po Valley. Book for lunch rather than late evening.
If you are driving through the Po Valley and want a genuinely rooted meal at a price that does not hurt, Da Manuela in Isola Sant'Antonio is worth the detour. The Michelin Plate recognition (2025) and a Google rating of 4.7 across more than 1,300 reviews place this well above the baseline for regional trattorie in the area. At the €€ price point, it delivers Lower Piedmont and Lomellina cooking that you would struggle to find prepared this honestly in a larger city. Book it for lunch or an early dinner; this is not a late-night destination, and planning around that reality will save you a wasted trip.
Da Manuela sits in the flat agricultural country where Piedmont meets Lombardy, a corridor defined by rice paddies, river channels, and traditions of cucina povera that predate the tourist circuit entirely. The cooking here draws on two overlapping regional identities: the Lower Piedmont repertoire, with its reliance on rabbit, seasonal vegetables, and aged cheeses, and the Lomellina tradition, which brings freshwater fish and frogs' legs to the table. These are not items you find treated seriously in most Italian restaurants outside this specific geography, which is precisely what makes the drive worthwhile for a food-focused traveller.
The physical setting reads as a country dining room rather than a polished restaurant. Spatial expectations should be calibrated accordingly: this is a room built for the rhythms of a rural Italian lunch, with the intimacy of a family-run trattoria rather than the theatre of a destination dining room. Seating is table-based and communal in atmosphere, suited to groups of two to six who want to eat at their own pace rather than move through a timed experience. The scale is modest, which means the room fills and the pace is set by the kitchen, not by a ticketed reservation system.
The Michelin Plate, awarded in 2025, is a signal worth reading carefully. It marks a restaurant that Michelin inspectors find worth knowing about, even where the cooking does not pursue the formal ambitions of starred cuisine. For this category of regional country cooking, the distinction is meaningful: it tells you the fundamentals are being executed correctly and that the kitchen takes its sourcing and preparation seriously. Piazza Duomo in Alba and Dal Pescatore in Runate both represent what happens when this regional tradition is taken to a starred level of formality and cost; Da Manuela sits at the honest, affordable end of the same culinary spectrum.
Menu anchors on rabbit with vegetables as a signature of the Lower Piedmont tradition, alongside the freshwater fish dishes and frogs' legs that mark the Lomellina influence. The cheese selection is noted in the Michelin entry as particularly strong, which in this region means aged local varieties that rarely make it onto export markets or urban restaurant menus. The wine list is described as excellent, and in this part of northern Italy that typically means a focused selection of Piedmontese labels, probably including Barbera d'Asti and Grignolino, at prices that reflect a local rather than a destination-restaurant markup. For a food and wine traveller exploring beyond the Barolo and Barbaresco circuit, that combination has clear appeal.
On timing and late-evening options: Da Manuela is not equipped for the role of late-night dining destination. Country trattorie in this part of Italy operate on agricultural rhythms, with lunch often the primary service. If your schedule requires dining after 9 PM, this is not the booking to make; consider it instead for a long, unhurried lunch or an early dinner that lets you settle into the pace the kitchen is built for. Travellers routing through the area should plan accordingly, building the meal into a daytime itinerary rather than an evening programme. For a broader picture of what else the area offers, see our full Isola Sant'Antonio restaurants guide, bars guide, and hotels guide for overnight options that make the trip more practical.
Two comparable country cooking destinations in the wider region worth knowing about: 21.9 in Piobesi d'Alba and Andrea Monesi - Locanda di Orta in Orta San Giulio both work the same regional tradition at roughly comparable price points. If your route takes you through Piemonte more broadly, Locanda di Orta pairs well with a lake stop; Da Manuela is the better call if you are specifically in the Po plain and want a kitchen rooted in that geography rather than adapting to a tourist audience.
For the traveller who cares about eating food that is specific to where they are standing, Da Manuela delivers exactly that at a price that leaves no buyer's remorse. The 4.7 rating from over 1,385 reviewers is not accidental; this is a kitchen that has maintained consistency over many covers. Book it, go at lunch if you can, and arrive with appetite for cheese.
Reservations: Easy to secure; call ahead or book early in the week for weekend lunch slots. Budget: €€, making this one of the more accessible Michelin-recognised stops in the region. Leading timing: Lunch is the primary service; plan your visit around midday rather than late evening. Getting there: The address references the bridge road (Via Ponte sul Po, 31, Capraglia AL); use a digital navigator as the Michelin entry suggests. Dress: No formal dress expectations; country casual is appropriate for the setting. Group size: Works for pairs and small groups; the room is intimate in scale. Explore local wineries and experiences in Isola Sant'Antonio to build a full day around the meal.
Comparing Da Manuela directly to Osteria Francescana in Modena, Reale in Castel di Sangro, or Atelier Moessmer Norbert Niederkofler in Brunico is not quite the right exercise: those are all €€€€ destinations built around ambitious, chef-driven tasting menus that require planning months in advance and a budget to match. Da Manuela operates in a different category entirely, one where the point is regional fidelity and value rather than creative ambition. If you want to spend a significant amount on an Italian fine dining experience, those venues will give you a fundamentally different type of meal.
Within the Italian country cooking category, the more relevant comparison is with Dal Pescatore in Runate, which also operates in the Po Valley tradition but at the €€€€ level with three Michelin stars and a booking difficulty that requires lead time of weeks or months. Da Manuela is the practical alternative if Dal Pescatore is unavailable, out of budget, or not the right format for your trip. You trade formal service and a deeper wine programme for accessibility, lower spend, and a room that feels lived-in rather than curated. Quattro Passi in Marina del Cantone offers a similarly regional anchor but on the southern Italian coast, so geography determines that choice rather than quality or price.
For the explorer who wants to work through Italy's regional cooking traditions without defaulting to starred venues, Da Manuela gives you the Lomellina and Lower Piedmont chapter at a price that allows several meals per trip rather than one centrepiece booking. That is a genuine advantage. If the tasting menu format and a larger wine programme matter more to you, Le Calandre in Rubano or Enrico Bartolini in Milan are the direction to look, at considerably higher cost and booking complexity.
| Venue | Cuisine | Awards | Booking Difficulty | Value |
|---|---|---|---|---|
| Da Manuela | Country cooking | Specialities from Lower Piedmont and the Lomellina region (such as the excellent rabbit with vegetables) are accompanied by a few freshwater fish dishes and traditional frogs’ legs on the menu at this restaurant, which also offers a fine array of delicious cheeses. The wine selection is also excellent.; Michelin Plate (2025); Specialities from Lower Piedmont and the Lomellina region are accompanied by a few freshwater fish dishes and traditional frogs’ legs on the menu at this restaurant, which also offers a fine array of delicious cheeses. The wine selection is also excellent. | Easy | — |
| Atelier Moessmer Norbert Niederkofler | Italian, Creative | Michelin 3 Star, World's 50 Best | Unknown | — |
| Dal Pescatore | Italian, Italian Contemporary | Michelin 3 Star, World's 50 Best | Unknown | — |
| Osteria Francescana | Progressive Italian, Creative | Michelin 3 Star, World's 50 Best | Unknown | — |
| Quattro Passi | Italian, Mediterranean Cuisine | Michelin 3 Star, World's 50 Best | Unknown | — |
| Reale | Progressive Italian, Modern Cuisine | Michelin 3 Star, World's 50 Best | Unknown | — |
Comparing your options in Isola Sant'Antonio for this tier.
Yes, and arguably better suited to solo diners than larger groups. A €€ price point means you can order broadly without anxiety, and the country cooking format — regional dishes like rabbit with vegetables, freshwater fish, and a strong cheese selection — rewards a curious, unhurried solo diner more than a table trying to split things evenly.
Bar seating details are not confirmed for Da Manuela. For a venue of this type in rural Piedmont, table service is the standard format. Call ahead to ask about seating options, especially for a quick meal rather than a full sit-down.
The menu leans heavily on regional animal proteins — rabbit, frogs' legs, freshwater fish, and aged cheeses — so plant-based or strict vegetarian diners will find limited options. The cheese selection offers an out, but this is not the right venue if meat and fish are off the table entirely. Call ahead if you have specific needs.
It works well for a low-key celebration where the meal itself is the occasion — a birthday lunch, an anniversary for people who prefer substance over staging. The Michelin Plate recognition and the depth of the regional menu give it enough credibility for that. If you need a grand room or a long wine programme, look to Dal Pescatore in Canneto sull'Oglio instead.
At €€, yes. A Michelin Plate restaurant at this price bracket in rural Piedmont represents genuine value. You are getting Lower Piedmont and Lomellina specialities — rabbit, freshwater fish, frogs' legs, and a noted cheese board — at a cost that most comparable venues in larger Italian cities would not match.
A dedicated tasting menu is not confirmed in the available information for Da Manuela. The kitchen's strength appears to be in its à la carte regional dishes. Order across the menu — a first course, a regional main like the rabbit with vegetables, and close with the cheese selection — rather than waiting for a set format.
Dal Pescatore in Canneto sull'Oglio is the closest meaningful comparison in the broader Po Valley corridor — three Michelin stars, a much higher price, and a more formal room. For something closer in register and budget, look to other Michelin Plate-level trattorias in the Alessandria and Pavia provinces. Da Manuela has a distinct Lomellina angle that is hard to replicate directly.
Keep this venue in your Pearl passport, rate it after you visit, and track it alongside every other place you collect.
